I recommend you already have a chilled beverage at your side before you start the run.
Then you can relax and watch Seinfeld reruns on your 2nd monitor while you play. ![]()
I’ll need some time to hammer out variants and an endgame config, but I am pretty certain you can cut down kill times a fair bit with good legendaries and better (but realistic) affixes on the greens.
Or you can spec into sth with hefty DPS instead of massive regen, like this one:
Leviathan/Warborn Witchblade by sk_choi