Maybe a program that significantly reduces number of buttons could be of use to you [Tool] GDAutocaster - play 🎹 builds with ease, autocasting of skills, combos, faster / automatic camera, autohiding of items, centered Inquisitor Seal and more for all games!
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For example a build with 9 buttons can be often made to just need 2 buttons, i.e. LMB + RMB
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Temporary buffs starts are autocast periodically after you launch the game.
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All permabuffs are cast with 1 button
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Debuffs can be set up to be cast after you press RMB once one after another
and if you keep holding you use your spam attack afterwards. -
Movement skills can be made to me spammed after double LMB click & hold.
I assume a tablet with a drawing pen could be used with this program so that you can use just that?
Or learn to use mouse with your left hand and use just that (with the program above)?