I conquered pioneer difficulty, what are some things that work in pioneer but don't work in Trailblazer difficulty and above?

Title essentially, do the higher difficulties mean you have to explore more of the map earlier on and have longer travel times on gathering resources?

What are some things that work on pioneer but don’t work on trailblazer difficulty?

everything works the same.

its just less ressources at the start
faster spread and more often deseases
more predators
more and harder raiders and armies

and you could choose harder maps with less ressources or less furtile land

it’s actually all explained in the tooltips when you start a new city