Sorry about that, I went overboard with my previous rant. I didn’t mean it, but it seemed funny how you could be in need of those particular ingredients that much.
As is only SoT doesn’t give you neither Blood, nor Brain matter however BoC compensates for that and every run gives you more bloods than what you entered it with. So when you go to SoT you are doing it knowing you are going there for something else than the mats, meaning don’t go there if you are not hunting for something specific that drops only there.
Giving your hard earned bloods and hearths and brains 
to the legendary blacksmith is a scam. If you were to craft legendary level 75 you know almost exactly what you are getting. When you go to the blacksmith you have to craft so many times that it’s not worth it. For me at least.
There is no fast way to the legendaries you need and once you exhaust your ingredients it becomes apparent how slow their accumulation can be.
So you wanting to constantly craft more leggies and having enough for keys is just greedy. However once you start doing it you obtain what you need for future builds and at some point you don’t need that many items. Eventually even the rare ingredients pile up… if you stop crafting unnecessary legendaries since you have other means to obtain them.