PS: This is not a whole guide but merely a showcase.
Image from the game with perma buffs
Amulet and gloves are crafted with slow resist.
GRIMTOOLS
SR 75-76 Complete Run
SR 85 Complete Run (Kaisan and IM)
SR 85 Complete Run (Grava and Valdaran)
Avatar of Mogdrogen
No change maded. Used health, OA&DA, lightning resist and lifesteal consumables. Added cluster to the bar but didn’t need it.
Crate of Entertainment
No change maded. Used health, OA&DA, health regen consumables, used aether cluster at the end to be safe.
PS: Tried Ravager of Minds several times but it’s really a hard combat. Possible but requires some nerves and good timing which means including GI that I don’t use.