They are outside of my scope, you need to sacrifice damage and build specifically for those deep shards which I find boring as you are just putting most of your eggs into defenses basket. Plus there are some build types, namely pets, that are much better suited for those deep SR dives.
This kind of build needs to stand still a lot and while it can facetank Calla and even eat her first stage sunders SR 38 would be too much. I guess you can tweak it for those shards and shit out armor from somewhere as well as more hp but as I said there are better builds for these exotic challenges (asides from pets I would guess that some kind of a tanked up Arcanist that can kite and do damage would be a better candidate).