Here goes: Warder, Level 100 (GD 1.2.1.3) - Grim Dawn Build Calculator
(Drawing liberal inspiration from @mad_lee’s Blitz Warlord, tweaked to fit OP’s needs.)
Just ran a few maps with it, killed 2 nemesis and Korvak, never saw my health dip below 3/4, and I wasn’t really paying attention. (20k health, 6k health regen, 18% absorb, 35% physical resist, 25% DR and 3.5k armor will do that)
I needed to access the keyboard once to summon my wind devils, but after that, it was all one-handed. (I have hotkeys 7 and 8 bound to side buttons on my mouse)
Most of the key pieces are either target-farmable (Helmet, Amulet, mace, shield) or craftable (Avenger set) And the target to farm are almost all accessible very early in the game (except Bargoll)
Prefixes are optimized (sorta) for the purpose of this link, but basically anything relevant would do. (I don’t actually have those exact affixes on my own character anyway)
Damage is a bit lacking, and the build could probably be tuned a bit more in that sense with a small compromise on sustain. Think of this as a starting point.
This build could very easily be made as a commando or Witchblade too, the former having even less buttons to press but also less RR, the later having the opposite.
Enjoy!