Sorry, don’t have any specific builds in mind but here’s a few opinions from a 2H-only player. 
Mastery-wise, 2H kinda sucks at times. 2H savagery is great with the transmuter, so is forcewave and PS. But then you have Word of Renewal’s 2H transmuter which only reduces a 15s CD to 12s. Why?
Gear-wise, items like Titan Pauldrons (https://www.grimtools.com/db/items/9207) are great. But they tend to be limited to a few damage types, mostly physical. There’s more to 2H builds than Shaman/Soldier, guys.
Soulrend
https://www.grimtools.com/db/items/9433
Great item, but potential for more. It should really have some support for necromancer, if only because it’s a freaking scythe for grim reaper cosplaying. Not to mention the flavor text “…devourer of souls”. Plus 2H bone harvest exists, with the awesome cold transmuter. Incidentally, necromancer supports cold in DE and BH, but there’s no -% cold res to be found, not even in the chillwhisper set. A +1 to necro would be cool, just like Bane of the Winter King has +1 Shaman.
Rancor
https://www.grimtools.com/db/items/11701
Nadaan’s Reach
https://www.grimtools.com/db/items/12700
Love them both, but they are too similar in my opinion. TWO new swords and they both support only pierce? Remember that the pierce can’t be converted to anything else either. How about cold/acid RoS or ABB. Missed potential there, I know pierce needed support but why two NB pierce swords? Why not pierce RoH infil, or pierce forcewave soldier, for example.
Alkamos Scythe
https://www.grimtools.com/db/items/8768
Alkamos Warsword
https://www.grimtools.com/db/items/8774
The warsword is the real star of the show with the conversion on PB, this opens up so many build possibilities. On top of already supporting the OK mastery. The Scythe… just kinda gives you blitz. And not much else. Some other crazy conversion would be nice, or at least another modifier.
Honorary mention to Cesarin’s Conviction
https://www.grimtools.com/db/items/8795
“50% Lightning Damage converted to Physical Damage”
Clearly meant to support physical. But the weapon has 25% armor piercing that you can’t get rid of. Self-inflicted debuff? :rolleyes: